Miriam Cnop Selected Research

tRNA Methyltransferases

11/2018	Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes.
10/2013	tRNA methyltransferase homolog gene TRMT10A mutation in young onset diabetes and primary microcephaly in humans.

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Miriam Cnop Research Topics

Disease

28	Type 2 Diabetes Mellitus (MODY) 01/2021 - 07/2002
17	Obesity 01/2022 - 04/2002
17	Insulin Resistance 01/2021 - 04/2002
9	Inflammation (Inflammations) 10/2021 - 04/2008
9	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2020 - 11/2005
5	Friedreich Ataxia (Friedreich's Ataxia) 01/2020 - 07/2009
3	Microcephaly 11/2018 - 10/2013
3	Necrosis 01/2016 - 04/2002
2	Chronic Pancreatitis 01/2021 - 05/2015
2	Weight Loss (Weight Reduction) 12/2020 - 04/2017
2	Non-alcoholic Fatty Liver Disease 04/2017 - 09/2011
2	Glucose Intolerance 01/2017 - 07/2002
2	Hyperglycemia 01/2016 - 10/2014
2	B-Cell Lymphoma (Lymphoma, B Cell) 10/2014 - 02/2011
1	Mental Disorders (Mental Disorder) 12/2021
1	Mood Disorders (Mood Disorder) 12/2021
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2021
1	Pancreatic Diseases (Pancreatic Disease) 01/2021
1	Feeding and Eating Disorders (Eating Disorder) 01/2021
1	Diabetes Mellitus 01/2021
1	Binge-Eating Disorder (Binge Eating Disorder) 01/2021
1	Body Weight (Weight, Body) 08/2020
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2020
1	Glaucoma 01/2018
1	Alzheimer Disease (Alzheimer's Disease) 01/2018
1	Critical Illness (Critically Ill) 01/2018
1	Hypoglycemia (Reactive Hypoglycemia) 01/2018
1	Morbid Obesity 04/2017
1	Bardet-Biedl Syndrome (Syndrome, Bardet-Biedl) 04/2017
1	Intellectual Disability (Idiocy) 11/2015
1	Wolcott-Rallison syndrome 11/2015
1	Rare Diseases (Rare Disease) 04/2015
1	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2012
1	Autoimmune Diseases (Autoimmune Disease) 01/2012
1	Type 8 Maturity-Onset Diabetes of the Young with Exocrine Dysfunction 10/2011
1	Lipomatosis 10/2011
1	Proteostasis Deficiencies 10/2011
1	Mason-Type Diabetes 10/2011
1	Liver Failure 01/2010
1	Martinez-Frias Syndrome 01/2010

Drug/Important Bio-Agent (IBA)

15	Insulin (Novolin)FDA Link 10/2021 - 04/2002
14	Glucose (Dextrose)FDA LinkGeneric 10/2021 - 07/2002
11	CytokinesIBA 01/2021 - 11/2004
11	Nonesterified Fatty Acids (NEFA)IBA 08/2020 - 04/2002
7	Proteins (Proteins, Gene)FDA Link 10/2021 - 12/2010
5	Inulin FDA Link 01/2022 - 11/2020
4	PalmitatesIBA 08/2020 - 04/2002
4	Oleic Acid (Oleate)IBA 01/2020 - 04/2002
4	FrataxinIBA 01/2020 - 07/2009
3	PrebioticsIBA 09/2021 - 11/2020
3	Transfer RNA (tRNA)IBA 01/2021 - 10/2013
3	Lipase (Acid Lipase)FDA Link 01/2021 - 10/2011
3	Fatty Acids (Saturated Fatty Acids)IBA 08/2011 - 02/2008
3	PPAR gammaIBA 07/2009 - 04/2002
2	Biological ProductsIBA 12/2021 - 01/2021
2	LipidsIBA 09/2021 - 01/2020
2	EstersIBA 01/2021 - 10/2011
2	IronIBA 01/2020 - 01/2010
2	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 10/2017
2	FructoseIBA 01/2020 - 10/2014
2	tRNA MethyltransferasesIBA 11/2018 - 10/2013
2	FatsIBA 01/2012 - 06/2008
2	AdipokinesIBA 01/2012 - 12/2003
2	LeptinIBA 01/2012 - 04/2002
2	InterferonsIBA 02/2011 - 12/2005
2	Transcription Factors (Transcription Factor)IBA 02/2011 - 07/2009
2	Interferon-gamma (Interferon, gamma)IBA 06/2009 - 02/2008
2	NF-kappa B (NF-kB)IBA 12/2005 - 11/2005
1	Monocyte Chemoattractant ProteinsIBA 10/2021
1	Ribonucleases (Ribonuclease)IBA 10/2021
1	Leukocyte L1 Antigen Complex (Calgranulin)IBA 09/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	XenobioticsIBA 12/2020
1	Peptides (Polypeptides)IBA 08/2020
1	Triglycerides (Triacylglycerol)IBA 08/2020
1	AdiponectinIBA 08/2020
1	SulfurIBA 01/2020
1	IncretinsIBA 01/2020
1	Exenatide (Byetta)FDA Link 01/2020
1	palmitoleic acidIBA 01/2020
1	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2020
1	Glucagon-Like Peptide-1 Receptor AgonistsIBA 01/2020
1	Messenger RNA (mRNA)IBA 01/2020
1	Protein Isoforms (Isoforms)IBA 01/2018
1	Guanabenz (BR 750)FDA Link 01/2017
1	Streptozocin (Streptozotocin)FDA Link 01/2016
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 11/2015
1	Phosphotransferases (Kinase)IBA 11/2015
1	Protease Inhibitors (Protease Inhibitor)IBA 05/2015
1	Peptide Hydrolases (Proteases)FDA Link 05/2015
1	ChemokinesIBA 12/2013
1	Bcl-2-Like Protein 11IBA 05/2013
1	Mutant Proteins (Protein, Mutant)IBA 10/2011
1	ProlactinIBA 02/2011

Therapy/Procedure

4	Therapeutics 12/2018 - 02/2007
2	Glycemic Control 01/2018 - 04/2017
1	Artificial Pancreas 01/2018
1	Bariatric Surgery 04/2017
1	Gastrectomy 04/2017
1	Transplantation 02/2011